Tamoxifen (alternative name Nolvadex, unofficially Tamox) was originally developed to treat women. Its medical purpose is to prevent the development of malignancies in the mammary gland. Today, the drug is actively used among athletes. In bodybuilding, the drug is used to reduce estrogen levels and prevent gynecomastia in men. Some athletes combine it with taking anabolics, while others take it as a restorative after the steroid cycle.
Using Nolvadex – tamoxifen in bodybuilding
Nolvadex (tamoxifen) does not affect blood levels of estrogen, but its mechanism of action also consists of a blockade of estrogen receptors, including in the pituitary gland. However, Clomid is a more selective blocker and Nolvadex is less selective. While Clomid binds to estrogen receptors primarily in the pituitary and testicles, Nolvadex binds to them virtually throughout the body. The exception is bone tissue where Clomid and tamoxifen on the contrary activate estrogen receptors.
It is most rational to use aromatase inhibitors during a course, among which Proviron is especially popular, as this drug does not affect negatively the secretion of growth hormone and increases the concentration of anabolic hormones in the blood due to suppression of aromatization. On the last week of the course and 7 weeks after it should be used Tamoxifen, as the main component of PCT In the absence of Proviron, the beginning of Nolvadex is in the 7th week of the steroid cycle, and ends 7-8 weeks after the end of the cycle, the average dose is 65-75 mg per day. I would like to pay special attention to the widespread misconception that anti-estrogens are recommended to drink after a cycle. Estrogen level raises at the end of the first week of a cycle, therefore since this moment, it is necessary to begin reception!
Anabolic drugs can only be used as prescribed by a doctor and are contraindicated in children. The information provided does not call for the use or distribution of potent substances and is aimed solely at reducing the risk of complications and side effects.
Tamoxifen citrate, better known by its brand name Nolvadex (Nolvadex), is commonly prescribed to treat and prevent breast cancer in women. Nolvadex acts as an estrogen-receptor blocker. Nolvadex has proven to be a safe and effective drug in the treatment of breast cancer, especially in older women who have a large number of estrogen receptor cells in their breasts. Nolvadex has gained popularity among bodybuilders using anabolic steroids because of its ability to block the effects of estrogen.
Nolvadex is a drug that is classified as an anti-estrogen. It is most commonly used in the treatment of breast cancer, but it also has benefits for bodybuilders. One of the benefits of Nolvadex is that it can help to prevent gynecomastia, or the development of breasts in men. It can also help to reduce water retention and bloating, which can make athletes look more streamlined and muscular. Additionally, Nolvadex can increase testosterone levels by blocking the effects of estrogen in the body. This can lead to increased muscle mass and strength.
Side effects of Nolvadex in bodybuilding, contraindications
Nolvadex should not be used during pregnancy. There are a small number of reports regarding cases of spontaneous abortions, birth defects, and intrauterine death after women take Nolvadex, although a causal relationship has not been established. Reproductive toxicology studies in rats, rabbits, and monkeys have shown no potential teratogenic effects.
In rodent individuals studied for fetal reproductive tract development, tamoxifen was associated with changes similar to those caused by estradiol, ethinylestradiol, clomiphene, and diethyl stilbastrol (DES) exposure. Although the clinical correlation of these changes is unknown, some of them (especially vaginal adenosis) are similar to those seen in young women exposed to DES in utero and have a 1 in 1000 risk of vaginal or cervical clear-cell cancer. Only a small number of pregnant women were exposed to tamoxifen. In these cases, there are no reports of such exposure causing subsequent vaginal adenosis or clear cell vaginal or cervical cancer in young women exposed to tamoxifen.
In cases of sexual activity during Nolvadex, women should be advised to prevent pregnancy and to use barrier or other non-hormonal contraceptives. Premenopausal patients should be carefully screened to rule out the presence of pregnancy before treatment is initiated. In women, the potential risk to the fetus should be assessed if pregnancy occurs during the use of Nolvadex or within two months of discontinuation of therapy.
Tamoxifen and post cycle therapy
Many people use tamoxifen after a course of steroids due to its cheapness. The use allows the testicles to work faster and release their own testosterone. As a result: their own production of male hormone is normalized, due to this muscle mass is preserved. But here’s the catch. The direct function of tamoxifen is the extinguishing of estrogen levels in the body. And among its disadvantages are the delayed work of testicles, which indicates that the drug is not the best choice for PKT. For post-course therapy, there is a very effective drug – clomiphene citrate, which does its job perfectly and is considered more recommended for PKT. However, its cost is 2-3 times higher than that of tamoxifen, but the result is also much better.
To monitor the condition of the athlete, hormone tests (LH, FSH, estradiol, total testosterone) should be taken from day 15 of the first cycle and repeated every 2 weeks. Laboratory tests will help to adjust the days of taking Tamoxifen (other anti-estrogens), to minimize adverse reactions during and after the anabolic cycle. You should not save on the amount of the drug, it is always better to keep it in reserve. Also in the recovery period, male bodybuilders can benefit from Aromatase inhibitors. A course of Tamoxifen is combined with an intake of Arginine (6-10 grams per day), which is kept in the diet even after the cancellation of an anti-estrogen. Supplements with valuable amino acids contribute to fat burning, muscle building, cleansing the body of toxins, and accelerating recovery and healing after injuries.
In addition to synthetic drugs, you can replenish the substance by consuming foods with arginine: nuts, pumpkin seeds, uncooked rice, chicken eggs, milk, peas, and buckwheat bread. At the beginning of post-course therapy, a week’s rest with complete absence of physical exertion is done. At the end of this period and until full recovery, switch to averaged training. It is also necessary to observe the sleep regime, and supplement the diet with unsaturated fats, vegetables, and seafood. Throughout the recovery period, it is recommended to drink vitamin E (400 IU/day).