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This remedy somewhat falls out of the general range of drugs, as it is neither androgenic nor anabolic. And yet, it is worth advising as a necessary useful tool for bodybuilders, which consists and proves its wide range of effects and positive results. Nolvadex belongs to the group of sexual hormones and is an anti-estrogen. Normally, its scope of application is the treatment of certain forms of breast cancer in women. The drug stops the growth of malignant tumors and prevents the formation of new ones. The growth of certain types of tumors is caused by the hormone estrogen itself. This applies primarily to the mammary glands of men and women, because there are a large number of estrogen receptors, which can bind to estrogens in the blood. If the levels of estrogen in the blood are unusually high, unwanted breast growth can occur.
Why Nolvadex is more suitable for men
If blood estrogen levels are unusually high, unwanted breast growth may occur. Yet it is men who take it more often. At first glance it seems unbelievable, but a closer look at the drug makes everything clear, because Nolvadex is taken simultaneously with anabolic steroids. Since most steroids are more or less strongly aromatized, i.e. their active chemical substance is converted into estrogens, athletes can have elevated blood levels of estrogens, which are exceptionally low in the normal range. Various phenomena of feminization arise: gynecomastia, increased accumulation of fat, and increased accumulation of water in the body.
Anti-estrogen Nolvadex counteracts this by blocking estrogen receptors of body tissues, thus preventing the formation of “estrogen + receptor” compounds. Still, it is important to understand that Nolvadex does not stop aromatization, but only blocks the body’s estrogen receptors for aromatized molecules, i.e., it is only an estrogen antagonist. This means that testosterone and its synthetic derivatives (steroids) are still subject to transformation into estrogens. The drug is only in eternal competition with them for estrogen receptors. This is also a disadvantage because after Nolvadex administration a “reverse effect” may occur, i.e. released estrogen receptors may start to collect estrogens accumulated in blood.
Therefore there is a sense to combine reception Nolvadex with Proviron (see Proviron). Nolvadex is good for dieting because it supports the fat burning process. Although it does not have a direct fat-burning property, it does, due to its anti-estrogenic effects, help keep the body as low in fat as possible. Nolvadex should have been taken together with the highly androgenic steroids Dianabol, Anapolon 50 or various testosterone variants.
Athletes prone to severe water accumulation in the body and with easily occurring problems with the breasts should use Nolvadex in any steroid course for prophylactic purposes. Since Nolvadex works very well in most cases, it is not surprising that some lifters take Anapolone and Dianabol right up until race day and in combination with some kind of diuretic. This allows them to appear firm and lean on stage. And those with already low-fat levels enjoy markedly improved muscle density with Nolvadex.
Nolvadex – tamoxifen side effects when used by men
With long-term treatment, side effects are not as numerous or as severe with Nolvadex as with androgens and estrogens, which are also used to treat breast cancer.
Reported side effects can be classified as arising either from the anti-estrogenic effects of the drug, such as hot flashes, vaginal bleeding, vaginal discharge, and external genital itching, or as more general side effects such as gastrointestinal intolerance, tumor recurrence, dizziness, skin rashes, and in some cases, fluid retention and alopecia.
If serious adverse events occur, they can be controlled by simply reducing the dose while still controlling the course of the disease. Hypercalcemia has been observed in a small number of patients with bone metastases during therapy.
In patients using Nolvadex to treat breast cancer, reductions in platelet counts to 80,000 to 90,000 per ccmm, and sometimes even lower, have usually been observed. Visual disturbances, including rare cases of corneal changes, cataracts, and retinopathy, have been noted in a number of patients using Nolvadex. Cystic ovarian swellings have occasionally been observed in women using Nolvadex in the premenopausal period.
Cases of leukopenia, sometimes associated with anemia and/or thrombocytopenia, have been observed after Nolvadex use. Neutropenia has been observed in rare cases; sometimes it can be very serious. Rare cases of thromboembolic events have occurred during therapy with Nolvadex. Although these events are known to occur more frequently in patients with a malignant course of the disease, a causal relationship with Nolvadex has not been established.
When Nolvadex is used in combination with cytotoxic agents, there is an increased risk of thromboembolic events. Nolvadex use is associated with changes in liver enzyme levels and, in rare cases, with more serious disorders, including fatty liver infiltration, cholestasis, and hepatitis.
Nolvadex – tamoxifen is a drug used by men to increase testosterone levels and muscle mass. The drug is also effective in the prevention of breast cancer in women. It blocks estrogen receptors in the body, preventing the hormone from attaching and stimulating the growth of tumors. Nolvadex – tamoxifen has been shown to be safe and effective when used by men for its intended purpose. It is important to follow the dosage recommendations and to contact a doctor if any adverse effects are experienced.
Contraindications to the drug
Nolvadex should not be used during pregnancy. There are few reports of spontaneous abortions, birth defects, and intrauterine death after administration of Nolvadex in women, although a causal relationship has not been established. Reproductive toxicology studies in rats, rabbits, and monkeys have shown no potential teratogenic effects.
In rodent individuals studied for fetal reproductive tract development, tamoxifen was associated with changes similar to those caused by estradiol, ethinylestradiol, clomiphene, and diethylstilbastrol (DES) exposure. Although the clinical correlation of these changes is unknown, some of them (especially vaginal adenosis) are similar to those seen in young women exposed to DES in utero and are at 1 in 1,000 risks for vaginal or cervical clear-cell cancer. Only a small number of pregnant women were exposed to tamoxifen. In these cases, there are no reports of such exposure causing subsequent vaginal adenosis or clear cell vaginal or cervical cancer in young women exposed to tamoxifen.
In cases of sexual activity during the use of Nolvadex, women should be advised to prevent pregnancy and to use barriers or other non-hormonal contraceptives. Premenopausal patients should be carefully screened to rule out the presence of pregnancy before treatment is initiated. In women, the potential risk to the fetus should be assessed if pregnancy occurs during the use of Nolvadex or within two months of discontinuation of therapy.
Nolvadex – tamoxifen is a drug that is used by both men and women. It is a powerful fat burner and has been shown to be effective in helping people lose weight. For men, it is important to follow the recommended dosage and cycle in order to get the most benefit from the drug.
There are several benefits of using Nolvadex – tamoxifen for weight loss. First, it helps to burn fat quickly and efficiently. Second, it helps to suppress appetite and cravings. This can help people stick to their diet plan and lose weight faster. Finally, it can help improve mood and energy levels, which can also help with weight loss.
When using Nolvadex – tamoxifen for weight loss, it is important to follow the recommended dosage and cycle.